The Brain and Spine Institute is made up of experts in the field of neuroscience in order to bring patients the best healthcare in East Tennessee for a full range of neurological diseases and disorders.
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We provide a comprehensive continuum of cancer services, including prevention, outreach, diagnostic, treatment and support services delivered by our highly skilled staff with compassion and care.
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The Center for Women & Children's Health is a hub for supporting women's and children's individual healthcare needs. The center provides support, research and unmatched patient-centered care.
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Emergency and Trauma Services is the only Level I Trauma Center in the area and serves as the tertiary referral center for medical care in East Tennessee, serving Knox County and 21 surrounding counties.
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The Heart Lung Vascular Institute brings together expertise in clinical care, teaching and research. Patients receive exceptional healthcare combined with patient-centered care.
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Lamellar ichthyosis
Definition
Lamellar ichthyosis is a rare skin condition that appears at birth and continues throughout a person's life.
Causes, incidence, and risk factors
Lamellar ichthyosis is passed down through families (inherited). Both parents must have at least one abnormal gene to pass it to their children.
Symptoms
A baby is born with a collodian membrane -- a shiny, waxy layer of skin that sheds within the first 2 weeks of life. Red, scaly skin remains underneath. It resembles the surface of a fish.
Signs and tests
Treatment
Moisturizers containing urea, ammonium lactate, or other alpha-hydroxy acids may help. Also, retinoid medications such as tazarotene may be used on the skin (topically).
Gene therapy to correct the genetic defect may be possible in the future.
Support Groups
Expectations (prognosis)
Complications
When the collodian membrane is shed, babies are at risk for infection.
Later in life, eye problems may occur because the eyes cannot close completely.
Calling your health care provider
Prevention
References
Morelli JG. Disorders of keratinization. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 657.
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