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We provide a comprehensive continuum of cancer services, including prevention, outreach, diagnostic, treatment and support services delivered by our highly skilled staff with compassion and care.
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The Center for Women & Children's Health is a hub for supporting women's and children's individual healthcare needs. The center provides support, research and unmatched patient-centered care.
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Emergency and Trauma Services is the only Level I Trauma Center in the area and serves as the tertiary referral center for medical care in East Tennessee, serving Knox County and 21 surrounding counties.
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The Heart Lung Vascular Institute brings together expertise in clinical care, teaching and research. Patients receive exceptional healthcare combined with patient-centered care.
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Fibrous dysplasia
Definition
Fibrous dysplasia is a bone disease that destroys and replaces normal bone with fibrous bone tissue. One or more bones can be affected.
Alternative Names
Inflammatory fibrous hyperplasia; Idiopathic fibrous hyperplasia
Causes, incidence, and risk factors
Fibrous dysplasia occurs in childhood, usually between ages 3 - 15. The condition does not run in families (not hereditary), and the cause is unknown.
Symptoms
- Bone pain
- Bone sores (lesions)
- Difficulty walking
- Endocrine gland problems
- Fractures or bone deformities (rare)
- Unusual skin color (pigmentation)
The bone lesions may stop when the child reaches puberty.
Signs and tests
The doctor will perform a physical examination. X-rays of bones are taken.
Treatment
There is no cure for fibrous dysplasia. Bone fractures or deformities are treated as appropriate. The patient is screened for endocrine disorders as needed.
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Expectations (prognosis)
The outlook depends on the severity of the condition and the symptoms that occur.
Complications
- Cushing's disease
- Gigantism or acromegaly
- Heart rhythm disturbance
- Hyperthyroidism
- Rickets
Calling your health care provider
Call your health care provider if your child has symptoms of this condition, such as repeated bone fractures and unexplained bone deformity.
Specialists in orthopedics, endocrinology, and genetics may be involved in your child's diagnosis and care.
Prevention
There is no known way to prevent fibrous dysplasia. Treatment aims to prevent complications, such as recurrent bone fractures, to help make the condition less severe.
References
Heck RS Jr. Benign bone tumors and nonneoplastic conditions simulating bone tumors. In: Canale ST, Beaty JH, eds. Campbell's Operative Orthopaedics. 11th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 20.
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