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Lupus anticoagulants are antibodies against substances in the lining of cells. These substances prevent blood clotting in a test tube. They are called phospholipids.
Persons with these antibodies may have an abnormally high risk of blood clotting.
Most often lupus anticoagulants are found in persons with diseases such as systemic lupus erythematosus (SLE).
Lupus anticoagulants may also occur if:
You have such conditions such as
Some people have no risk factors for this condition.
You may not have any symptoms. Symptoms that may occur include:
The following tests may be done:
Often, you will not need treatment if you do not have symptoms or if you have never had a blood clot in the past.
Take the following steps to help prevent blood clots from forming:
Your doctor may prescribe blood thinning medicines (such as heparin and warfarin) to help prevent blood clots:
Most of the time, outcome is good with proper treatment. Some people may have blood clots that are hard to control with treatments. Symptoms may recur.
Call your health care provider if you notice symptoms of a blood clot such as:
Harris ED, Budd RC, Genovese MC, Firestein GS, Sargent JS, Sledge CB. Kelley's Textbook of Rheumatology. 7th ed. St. Louis, Mo: WB Saunders; 2005.
Review Date: 1/22/2013
Reviewed By: Todd Gersten, MD, Hematology/Oncology, Palm Beach Cancer Institute, West Palm Beach, FL. Review provided by VeriMed Healthcare Network.Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.
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