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Leukocyte esterase
Definition
Leukocyte esterase is a urine test to look for white blood cells and other signs associated with infection.
Alternative Names
WBC esterase
How the test is performed
A clean catch urine sample is needed. See: Urine specimen - clean catch
How to prepare for the test
No special preparation is necessary for this test.
How the test will feel
The test will involve only normal urination, and there is no discomfort.
Why the test is performed
Leukocyte esterase is a screening test used to detect a substance that suggests there are white blood cells in the urine, which may mean you have a urinary tract infection.
This test is part of the routine urine dipstick test. If this test is positive, the urine should be examined under a microscope for white blood cells and other abnormalities associated with infection.
Normal Values
A negative test result is normal.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What abnormal results mean
An abnormal result indicates a possible urinary tract infection.
What the risks are
There are no risks.
Special considerations
The following may create a false positive result:
- Vaginal secretions (such as blood or heavy mucus discharge)
- Trichomonas infection (such as trichomoniasis)
False negative tests can be caused by:
- High levels of protein
- High levels of vitamin C
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).