Bone Marrow Transplant

A lab tech drops a test tube into a freezer with tweezers


The Transplant and Cellular Therapy (TCT) Program at The University of Tennessee Medical Center offers state of the art and cutting-edge therapies to treat patients with complex blood cancers and other blood disorders. Our team of transplant and cellular therapy experts provide compassionate and multidisciplinary care, creating an individualized treatment plan for each patient. Our treatment options include peripheral blood stem cell transplant, chimeric antigen receptor t-cell (CAR-T) therapies, and clinical trials involving Immune Effector Cell Therapies.

The TCT Program features a dedicated team including expert physicians, advanced practice providers, nurses, registered dieticians, social workers, financial counselors, nurse navigators and TCT Coordinators ensuring the highest level of care throughout your entire treatment journey. Our physician team led by Kelly McCaul, MD, has nearly 30 years of experience treating patients with complex blood cancers. Our team works closely with your referring provider, delivering seamless coordination of care with your entire care team.

Intensive inpatient and outpatient care pre and post TCT requires time away from home for extended periods of time; often a barrier to receiving this treatment. UT Medical Center is honored to bring these services to patients from East Tennessee and beyond, offering convenient, high quality, community-based access to complex blood cancer care. The program will also bring access to cutting edge cellular therapy based clinical trials for the patients in the region. You can stay close to home and your support network while you benefit from the many years of experience held by our TCT specialists.

Watch the video below to learn more about our Transplant and Cellular Therapy team.

Conditions Treated

Peripheral blood stem cell transplant can benefit patients with the following conditions:

  • Leukemia
  • Non-Hodgkin Lymphoma
  • Hodgkin Lymphoma
  • Multiple Myeloma
  • Myelodysplastic/myeloproliferative disorders
  • Certain specific solid tumors
  • Other blood related disorders, such as Aplastic Anemia

Peripheral blood stem cell transplants are usually reserved for patients who have a high risk of relapsing, have already relapsed, or whose quality of life can be improved by a bone marrow transplant.

CAR-T (Chimeric Antigen Receptor T-cell) advanced cellular therapy, is a specialized form of immunotherapy using genetically engineered T-cells to target specific cancer proteins, killing said cancer cells. Currently, CAR-T benefits patients with different forms of lymphoid cancer including:

  • Non-Hodgkin Lymphoma
  • B Cell Lymphoma
  • Follicular Lymphoma
  • Mantle Cell Lymphoma
  • Acute Lymphoblastic Leukemia


Your Care at the Cancer Institute

The Cancer Institute at The University of Tennessee Medical Center offers the broadest spectrum of cancer specialists and services to care for our patients with complex blood cancers. Cancer patients can receive all of their cancer care including surgical consultations, genetic counseling/testing, chemotherapy infusions, radiation oncology, and supportive/integrative health services, all in the same building.

Our dedicated inpatient TCT unit is located on 5 West within The University of Tennessee Medical Center. The unit includes:

  • 9 Transplant/Cell Therapy Rooms- HEPA-ventilated inpatient rooms for transplant procedure and hospitalization
  • Outpatient Center- Dedicated outpatient space for apheresis (stem cell collection) and infusion services.
  • Onsite Lab- Dedicated lab for cell processing and separation.

Patients are reviewed at our weekly TCT and multidisciplinary conferences where surgeons, medical oncologists, radiation oncologists, radiologists, pathologists, genetic counselors, palliative care, nurses and clinical trial coordinators gather to determine the best individualized treatment plan for each patient. This level of coordination ensures that patients are receiving the highest level of care, offering the best outcomes and quality of life.

Our team cares for the patient as a whole and designs a medical care plan to meet their needs. Several key factors, such as the type and stage of the cancer, as well as age, health, and lifestyle are considered when determining each treatment plan.